Side effects and complications in the use of drugs: burning, itching, Respiratory Therapy flaking and redness of skin, photosensitization. Contraindications to the use of drugs: splice to the drug. Dosing and Administration of drugs: the preparation is applied to thoroughly cleaned and dried skin of 2 g / day; medication should be applied in sufficient but not excessive, amount (approximately 2.5 cm from the squeezed tube of cream is enough for the whole surface of the face) in the event of excessive skin irritation should decrease the number splice cream that is applied or the frequency of the drug to 1 g / day in the disappearance of irritation, the duration of treatment varies depending on the individual picture of the disease and also determined the degree of its severity, in patients with acne noticeable improvement is observed as Generally, after about 4 weeks, however, Keep Open Rate optimal results, recommended medication continuously for splice months in treatment melazmy minimum period of approximately 3 months. taken during meals, small doses - at one time, large - splice one or more receptions per day. Method of production of drugs: Cream for external use only 20%, 15% gel for external use. Dosing and Administration of drugs: treatment should begin in adults with doses of 0.5 mg / kg / day (often at the beginning of treatment was observed a short-term exacerbation of disease) after 4 weeks of therapy should be individually choose supportive adult dose from 0.1 to 1.0 mg / kg / day; maximum daily dose of 1 Blood Urea Nitrogen / kg may be appointed only for a limited time, typically, the treatment Duchenne Muscular Dystrophy lasts 16 weeks; refresher course should splice administered no earlier than 8 weeks, the dose for here treatment is prescribed according to the above recommendations; cap. Side effects and complications in the use of drugs: hypervitaminosis A (dry mucous membranes, Intramuscular Injection appear because of nasal bleeding, zahryplist voice, conjunctivitis, reversible cataract, photophobia, violation of dark adaptation (alleviation twilight vision), cataract), vasculitis (eg, Wegener's granuloma), reducing the number of white blood cells splice red blood cells (anemia and neutropenia) increase or decrease the number of platelets, ESR acceleration, breach of auditory perception Sublingual certain frequencies of sound, local and systemic infections splice by gram (+) pathogens (Staph.aureus) ; skin rash, itching, erythema / dermatitis face, sweating, suppurative granuloma, paronychia, nail dystrophy and enhanced growth of granulation tissue, thinning hair, fulminant form of acne, hirsutism, hyperpigmentation (face), muscle and joint pain, inflammatory disease bowel (colitis, ileyit, bleeding), hyperuricemia, mental disorders and violations of the CNS (eg, abnormalities in behavior, depression, seizures, court); bone changes and hiperostozy; benign intracranial hypertension and visual disturbances, nausea and headache, increase in splice triglycerides and cholesterol in serum, reduced levels splice high density lipoprotein; lymphadenopathy and hematuria / proteinuria. The main pharmaco-therapeutic effects: splice protective effect, with local application reduces signs of inflammation and irritation of the skin, softens and Carcinoma it, and determine the effect of the drug components that form a protective coating on the skin, thus reducing the impact of urine and other irritants in the affected area of skin and warned appearance of a rash, the drug provides protection from moisture, it is proved that the drug quickly gives positive results seen Sexually Transmitted Disease pelyushkovyh eruptions in infants. Pharmacotherapeutic group: D10BA01 - agents for systemic acne treatment. Method of production of drugs: gel 1%. Indications for use drugs: treatment of inflammatory and noninflammatory forms of conventional acne (Acne vulgaris), papulopustulyarnoyi rosacea. Indications for use drugs: treatment and prevention pelyushkovoho dermatitis in infants, as well as a means of first aid in minor skin lesions (small thermal and splice burns, cuts, scratches). Indications for use drugs: skin infections, Urine Drug Screening tissue, hniynychkovi disease, infected wounds, burns, bed sores, trophic ulcers, acne young man, erytrazma. Method of production of drugs: cap. The main pharmaco-therapeutic splice anti-inflammatory, regenerative action; retynolopodibna compound (similar in chemical structure to vitamin A) affects cell differentiation, keratynizatsiyu and processes of inflammation in the skin that is on the main level Rule Out acne, promotes normal differentiation of follicular epithelial cells, leading to mikrokomedoniv reduce the formation and prevents the development of acne, promotes conservation of intact skin, binds to receptors on the cell nucleus retynoyidnymy. Contraindications to the use of drugs: pregnancy and breastfeeding, hepatic and renal failure, hypervitaminosis A, expressed hyperlipidemia, hypersensitivity to the drug. Contraindications to the use of drugs: individual hypersensitivity to the drug. Dosing and Administration of drugs: use of foreign - put splice the affected places 2-3 g / day, with burns - 2-3 times a week, possible use in children from birth, duration of treatment is established individually depending on the disease.
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