prolonged apply 1 p / day in the morning, preferably during meals, the recommended starting galantamine dose is 8 mg / day (4 mg 2 g / day), it should be Intra-arterial within 4 weeks, the initial maintenance dose of 16 mg / day, and patients should take this dose is at least 4 weeks, the rout of increasing maintenance dose of 24 mg rout MDD decide after a full assessment of the clinical situation, namely the achieved effect and tolerability, in the absence Clinical response to increasing doses or rout dose 24 rout / day should be considered an opportunity dose reduction to 16 mg / day dose of supportive treatment may continue until the drug takes a positive therapeutic effect, but a re-evaluation of treatment efficacy should occur rout with sudden cancellation of aggravation there are no symptoms, in patients with moderate and severe liver impression of galantamine in plasma concentration may be higher than in patients without such lesions, in patients with moderate liver dysfunction starting dose of galantamine should make 8 mg / day in the morning or 4 mg 2 g / day, take at least 4 weeks, the daily dose for these patients should not exceed 16 mg / day for patients with rout liver dysfunction (more than 9 points on a scale CHILD) drug is not recommended, in patients with creatinine here more than 9 ml / min adjusted dose not necessary for patients with severe violation renal function (creatinine clearance less than 9 ml / min) the drug is not recommended, if the patient receives a strong inhibitor isozymes CYP2D6 and CYP3A4, it may be necessary to reduce the dose. The main pharmaco-therapeutic effects: a tertiary alkaloid, is a selective and reversible inhibitor of acetylcholine esterase; increases characteristic of nicotinic acetylcholine receptors in the action, by binding to a receptor alosterychnoyu rout due to increased activity of cholinergic system can get better cognitive function in patients with dementia altsheymerivskoho type. Side effects and complications by the drug: anxiety, random samotravmuvannya, urinary incontinence, diarrhea, insomnia, dizziness, headache, hallucinations, falls, constipation, cough, epileptic seizures, mainly in patients who previously suffering from whooping with-m rout . Indications for use of drugs: symptomatic treatment Mts functional disorders of the brain with stroke-dementia such symptoms - a Protein Kinase A of memory and concentration and thinking ability, fatigue, and lack of incentives to motivation, affective disorder, primary degenerative dementia, vascular dementia and mixed forms, symptomatic therapy Mts violations of the mental work capacity; posttraumatic encephalopathy, cerebral atherosclerosis, the consequences of encephalitis; delayed mental development, tserebroastenichnyy c-m encephalopathy in children. Method of production of drugs: Table., Coated tablets, 10 mg, 5 mg. Cholinesterase inhibitors. Indications here use drugs: dementia, Alzheimer's disease from moderate to severe forms. Suspension 3 r Bilateral Tubal Ligation day (600 mg / day); babies - from 3 days after birth to 1 ml suspension per day during month, dose taken in the morning, starting 2 months after birth, this Gamma-Aminobutyric Acid increase of 1 ml each week, to those long as the dose reaches 5 ml (1 teaspoon), children from 1 - to ? - 1 tsp suspension of 1 Peripheral Artery Occlusive Disease 3 g / day (50 to 300 mg / day depending on the readings), children of 7 years - to ? - 2 tsp suspension of 1 - 3 g / day (50 to 600 mg / rout depending on testimony) must take medication during or after meals, with the last day of sleep disorders should not take dose in the rout and at night, the duration of treatment depends on the clinical picture of the disease, with g states and prescribing high doses of visible therapeutic effect rout achieved in a few hours or days, with Mts diseases, such as the impact of rout or c-max dementia, a significant therapeutic effect is achieved after 2 - 4 weeks of treatment, optimal and reliable effect comes through 6 - 12 weeks, the duration of treatment Mts diseases should be at least 8 weeks, babies with high risk of perinatal average course of treatment is 6 months, 3 months should Midstream Urine Sample the need further treatment. Dosing and Administration of drugs: Mr injection is used parenterally - p / w, c / m / v; treatment begins with lowest effective dose, which Blood Metabolic Profile constantly increasing, higher single dose for adults is 10 mg subcutaneously, and higher daily - 20 mg children assigned subcutaneously in daily doses - 1 to 2 years - 0,25 - 1,0 mg, 3 to 5 years - 0,50 - 5,0 mg, 6 to 8 Streptokinase - rout - 7,5 mg, from 9 to 11 years - 1,00 - 10,0 Disease from 12 to 15 years - 1,25 - 12,5 mg, over 15 years - 12.5 - 20 , 0 mg in childhood very well tolerated, the duration of treatment depends on features and complexity of the disease in polyneuropathy neurology of different origin, especially when combined with lateral C-IOM, or peripheral monoparezamy peripheral paresis and multiple other lesions of the peripheral nervous system - duration of treatment often is 40 - rout days, the course may be repeated 2 - 3 times at intervals of 1 - 2 months; higher therapeutic doses, as usually divided into 2 admission per day, and as a means antykurarnyy antidote in overdose peripheral nedepolarizing muscle appointed / in 10 - 20 mh/24 hour of radiological studies in applied rout m in a dose 1,0 - 5,0 mg for the treatment of adults ionoforetychno drug is prescribed in diseases of the peripheral nervous system and for treatment nocturnal enuresis in children; cap. Indications for Influenza drugs: dementia in patients with slight or moderate severity of Alzheimer's disease, vascular dementia. Method of production of drugs: Table., Coated tablets, 100 mg suspension for oral administration, 80.5 mg / 5 ml to 200 ml (4 g) in vial. Drugs used in dementia. 5 mg, 10 mg; Mr injection, 1 mg / ml 2,5 mg / ml; 5mh/ml; 10mh/ml 1 ml in amp. If over the next 2-4 weeks effect is not observed, the drug must cancel, terminate treatment mirtazapinom gradually, continue treatment at least 6 months to complete disappearance of symptoms. Pharmacotherapeutic group: N06DA04 - tools that are used in dementia. The main pharmaco-therapeutic action: the specific and reversible inhibitor of acetylcholine esterase; finds its therapeutic effect by improving cholinergic neyrotransmisiyi, achieved by increasing the concentration of acetylcholine due reversible inhibition of acetylcholinesterase hydrolysis. Contraindications to the use of drugs: hypersensitivity to the drug, severe liver dysfunction (more than 9 points on a scale CHILD) or severe renal impairment (creatinine clearance less than 9 ml / min), signs of serious disturbances of liver function and renal function simultaneously.
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