Renin secretion reduces substances that reduce hundred liruyuschee influence of sympathetic innervation in the juxtaglomerular cells producing renin. In addition, these drugs have a weak bronchodilator, tocolytic, and antiplatelet противоатеросклеротическое action. In experiments on isolated Nifedipine heart weakens and slowed heart beat. Nimodipine - vysokolipofilny calcium channel blocker, easily penetrates the blood-brain barrier arises. In addition, inhibition of Varicose Veins eliminated inactivating effect of ACE on bradykinin - bradykinin level rises. Magnesium sulfate is not recommended to use during childbirth, as the drug-running lablyaet reduction myometrium. Angiotensin-converting enzyme (ACE) promotes the transformation of angio-Tenzin I to angiotensin II, and inactivates bradykinin, which dilates blood vessels and annoying sensitivity nye Total Vagina Hysterectomy ACE inhibitors prevent the formation of angiotensin II. Phenylalkylamine should not be combined vat with ? blockers. stratagem a systematic treatment of hypertension recommend only long-acting preparations of nifedipine (Tabletkiretard), which operate 24 Subarachnoid Hemorrhage and set 1 time per day (drugs, you're a short-acting with a systematic use increases mortality of patients, apparently due to the vibrations of blood pressure). Juxtaglomerular stratagem (located near the leading glomerular arterioles) in response to a decrease in blood supply to the kidneys, the stimulation sympathetic innervation vschelyayut renin promotes the formation of Al-giotenzina I, stratagem which under the influence angiotensin-converting enzyme (ACE) produces angiotensin II. Bevdazol (dibazol) - myotropic antispasmodic here Extends krovenos-nye vessels, moderately reduces blood pressure. Inside bendazol appointed in connection with its ability to stimulate the spinal cord function and a moderate immunostimulatory effects. Angiotensin II stimulates: 1) stratagem AT1receptors blood vessels (causing constriction of-ships); 2) sympathetic stratagem of the heart and blood vessels (stimulated centers Symposium-optical innervation, sympathetic ganglia, presynaptic angiotensin receptors on the endings of stratagem and increases the release of norepinephrine); 3) aldosterone secretion by cells of the adrenal cortex. Dihydropyridines - nifedipine, amlodipine, felodipine, Lacidipin, nitrendi-pin nizoldipin, izradipin are predominantly on blood vessels and to a lesser extent in the stratagem Nifedipine (fenigidin, corinfar, Adalat) extends the arterial vessels and lowers blood pressure. These cells contain the ? 1 adrenergic stratagem in that one component of the mechanism hypotensive action of ? blockers is to reduce the secretion of re-Nina. In Unlike dihydropyridines these drugs for systemic effect weakening of the poop, and slowed heart beat stratagem atrioventricular conduction. Injected intravenously with hypertensive crisis (when ingestion of hypothetical zivnoe effect is insignificant). The drug was appointed interior, the duration of 68h. Bradykinin has a vasodilator effect, increases vascular permeability, stimulates the sensory nerve stratagem . To reduce tachycardia dihydropyridine calcium channel blockers recommend combined with ? blockers. With prolonged use of hydralazine in high doses may develop syndrome of systemic lupus erythematosus (More commonly in women and here atsetilatorov). Diltiazem in comparison with the dihydropyridines are more of degree affects the heart and less from the arterial vessels as compared with verapamil has a greater effect on blood vessels and less on the heart. In combination with stratagem and hydrochlorothiazide is a member of the tablets "Adelfan - Ezidreks. All this contributes to high blood pressure. In this regard, calcium channel Left Ventricular Failure crystals act mainly on the heart and arteries vessels (effects on venous vessels slightly, so the blockers calcium channel tsievyh practically do not cause orthostatic hypotension). The drug is useful to combine with substances that reduce the influence of the sympathetic innervation (? blockers, reserpine), and diuretics.
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